Atletico Madrid host Manchester United in the first leg of their Champions League last-16 tie

This will be just the third time that the two teams have faced each other, with the last coming in the two-legged European Cup Winners’ Cup in 1991/92, so this means that United goalkeeper David de Gea will be making his first return to face his boyhood club.

Atleti vs Man Utd

Atletico Madrid host Manchester United in the first leg of their Champions League last-16 tie at the Estadio Wanda Metropolitano on Wednesday night. This will be just the third time that the two teams have faced each other, with the last coming in the two-legged European Cup Winners’ Cup in 1991/92, so this means that United goalkeeper David de Gea will be making his first return to face his boyhood club. Another familiar face set to return to the Spanish capital is Cristiano Ronaldo. He made history while playing for Real Madrid, with Atleti having terrible memories of the Portuguese forward. Edinson Cavani is a doubt to play for United in terms of team news, yet there is some good news for Ralf Rangnick as Eric Bailly is set to be in the squad.

For Atleti, Matheus Cunha is out after suffering a knee injury against Levante. Antoine Griezmann was an unused substitute in Los Rojiblancos’ 3-0 win at Osasuna last weekend so that he could get some minutes off the bench on Wednesday night. Koke is a doubt, though, while Yannick Carrasco is suspended for both legs.

Atletico Madrid vs Manchester United predicted line-ups

Atletico Madrid’s predicted line-up (3-5-2): Jan Oblak; Stefan Savic,Josema Gimenez, Reinildo; Sime Vrsaljko, Marcos Llorente, Koke, Geoffrey Kondogbia, Renan Lodi; Luis Suarez, Joao Felix.

Manchester United’s predicted line-up (4-3-3): David de Gea; Diogo Dalot, Raphael Varane, Harry Maguire, Alex Telles; Bruno Fernandes, Scott McTominay, Paul Pogba; Marcus Rashford, Cristiano Ronaldo, Jadon Sancho.

Atletico vs Manchester United kicks off at the Estadio Wanda Metropolitano on Wednesday, February 23 at 21:00 CET, the local time in Madrid. That makes it a 20:00 kick off GMT for anyone in the United Kingdom or for those in the United States; the game will start at 15:00 ET/midnight PT. Fans in the United Kingdom can tune in to watch Atletico vs Manchester United from 20:00 GMT on BT Sport 2 or on the BT Sport App. In the United States, meanwhile, European football fans will find Atletico vs Manchester United on Paramount , TUDNxtra, and the TUDN App.